Free Radicals

Free Radicals and Health




Free Radicals


Free Radicals in Biology and Medicine


Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing.
This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.



Free Radicals in Human Health and Disease


The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society.
The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.


Free Radicals and Health


This books reviews free radicals and health. Chapter One discusses the role of radicals in the impact of phenols on health and the environment. Chapter Two describes the very recent development of new synthetic phenol-containing polymers as effective free radical scavengers in aqueous environments, such as a phenolic resin (particularly novolac resin) grafted with hydrophilic poly(ethylene glycol) (PEG) by click chemistry. Chapter Three reviews the possible applications of radon therapy in veterinary care for oxidative stress-induced kidney damage. Chapter Four examines how melatonin could be taken into account as a drug with uses for cancer treatment in combination with the current chemotherapeutic drugs, reducing the dose of these agents and the toxicity for the patient. Chapter Five studies oxidative stress in rheumatoid arthritis. Chapter Six presents facts that review how the health benefits of many phytochemicals in natural beverages may be the consequence of hormetic effect and cross-resistance from the auto-oxidation of antioxidants leading to the formation of H2O2, which activates one or more adaptive stress response pathways.



Antioxidants Versus Free Radicals: A guide to a Healthy Long Life


The purpose of this book is to educate us on how diseases develop, learn the benefits and consequences of the decision we make of the food we eat and the lifestyle we choose in relation to our health and longevity.






Cellular Health Mitochondria Epigenetics DNA Testing Microbiota Gut Health
Stress Health Enzyme Functional Medicine Nutrition Antioxidants Supplements Amino Acids
Inflammation Anti-Inflammatory Butyrate Nucleotides GI-tract Health Short Chain Fatty Acids SCFAs
Oxidative Stress Vitamins Minerals Vagus Nerve Nutritional Supplements Leaky-Gut IBS Irritable Bowel Syndrome
Microbiome Gut Lining Probiotics Prebiotics Health Supplements Gut Supplements
Gut Mind Health Fiber Neurology Digestion Detox-Cleansing Digestive Health Wellness
Supplements Immune System Abdominal Health Brain Health Stomach Health Gut Microbiome












































































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Free Radicals and Health