Oxidative Stress

Oxidative Stress Nutrition for Improving Health

Oxidative Stress Nutrition

Nutrition and Epigenetics (Oxidative Stress and Disease)

Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text:
Documents the epigenetic effect of antioxidants and their health benefits
Adds to the understanding of mechanisms leading to disease susceptibility and healthy aging
Illustrates that the epigenetic origins of disease occur in early (fetal) development
Synthesizes the data regarding nutrient and epigenomic interactions
Nutrition and Epigenetics highlights the interactions among nutrients, epigenetics, and health, providing an essential resource for scientists and clinical researchers interested in nutrition, aging, and metabolic diseases.
About the Author
Emily Ho is the endowed director of the Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health. She is a full professor in the College of Public Health and Human Sciences, with an emphasis in nutrition, and is a principal investigator at the Linus Pauling Institute at Oregon State University. She joined the Oregon State University faculty in 2003 after receiving her Ph.D in human nutrition from the Ohio State University and completing her postdoctoral research at Childrenís Hospital Oakland Research Institute and UC Berkeley. During the course of her career, Dr. Ho has published 97 peer-reviewed articles and abstracts and four book chapters. She has been invited to give more than 40 presentations and has mentored more than 40 undergraduate and graduate students. She currently serves on the editorial board for Journal of Nutritional Biochemistry and Frontiers in Epigenomics. Her research interests are in the area of antioxidants and gene expression and dietary chemoprevention strategies. More specifically, she focuses on the effects of zinc status on DNA damage, DNA repair, and stressĖresponse signal pathways. Another major focus in her laboratory is investigating the genetic and epigenetic mechanisms by which foods such as soy, tea, and cruciferous vegetables may protect against prostate cancer.

Inflammation, Lifestyle and Chronic Diseases (Oxidative Stress and Disease)

Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to chronic diseases through inflammation. While short-term, acute inflammation generated by the immune system serves a therapeutic role, chronic low-level inflammation that may persist "silently" for decades is responsible for chronic diseases.
Inflammation, Lifestyle, and Chronic Diseases: The Silent Link describes the role of dysregulated inflammation in persistent and recurring diseases. It investigates links to lifestyle and presents research on how the suppression of proinflammatory pathways may provide opportunities for both prevention and treatment of chronic diseases. The book covers neurodegenerative diseases, pulmonary diseases, asthma, rheumatic and arthritic diseases, skin disease, heart disease, chronic wounds, infectious disease, neuropsychiatric disorders such as depression, gastrointestinal diseases, insulin resistance, and cancer, many of which are also diseases of old age.
For each chronic disease, contributors review the clinical and scientific literature and examine current and potential therapies, including conventional pharmacotherapies as well as natural products. Noting that the long-term use of steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause adverse side effects, many of the chapters address the role of dietary agents such as fruits, vegetables, legumes, pulses, nuts, and spices as ideal anti-inflammatory agents that can be consumed regularly. The book also suggests directions for further research. Clinical and science researchers, students, and health professionals interested in the link between inflammation, lifestyle, and chronic diseases will find this an informative resource.

Aging: Oxidative Stress and Dietary Antioxidants

Aging: Oxidative Stress and Dietary Antioxidants, Second Edition, bridges the trans-disciplinary divide and covers the science of oxidative stress in aging and the therapeutic use of natural antioxidants in the food matrix in a single volume. The second edition covers new trials and investigations used to determine the comprehensive properties of antioxidants, food items and extracts, as well as any adverse properties they may have. It has been updated to include new clinical human trials and a new section dedicated to animal models of aging. Throughtout the book the processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this.
Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging. This will aid in better research, treatment and outcome for patients.

Flavonoids and Related Compounds: Bioavailability and Function (Oxidative Stress and Disease)

Flavonoids exert a multiplicity of biological effects on humans and can have beneficial implications for numerous disease states. Flavonoids and Related Compounds: Bioavailability and Function examines current knowledge regarding the absorption, metabolism, and bioavailability of individual flavonoids and related phenolic compounds.
Profiling the latest evidence of their impact on various human pathological conditions, the book summarizes current thinking with regard to the biotransformation and conjugation of individual compounds in the gastrointestinal tract, liver, large intestine, and cells. It highlights a topic that has been largely ignored―namely the extent to which dietary phenolics components undergo metabolism in the large intestine. It also explores the generation of bacterially derived metabolites. Individual chapters discuss which metabolites enter the circulatory system and are likely to offer protective actions against human diseases.
Edited by internationally recognized leaders in the field, the book presents contributions by a panel of experts who demonstrate the potential of flavonoids in ameliorating a range of disease states, including cardiovascular disease, Alzheimerís and Parkinsonís disease and other neurodegenerative disorders, and cancer. The research presented in this volume provides a reliable starting point for further inquiry and experimentation.

Vitamin D: Oxidative Stress, Immunity, and Aging (Oxidative Stress and Disease)

Vitamin D insufficiency/deficiency is a worldwide, public health problem in both developed and developing countries. Rickets among infants has reemerged. Low levels of vitamin D are associated with increased risk and mortality from cancer. At the same time, the beneficial effects of vitamin D on a host of conditions have recently been discovered. Focusing on areas not extensively covered in other comparable books, Vitamin D: Oxidative Stress, Immunity, and Aging highlights the most recent research findings on the impact of this nutrient in oxidative stress, immunity, and aging.
A state-of-the-art compilation of essential information, this book explores:
Vitamin D and its genomic and nongenomic effects, the role of therapeutic analogs in treating disease, and the production of vitamin D by the body
The role vitamin D plays in modulating oxidative stress―with emphasis on cancer, stress-mediated diseases, photo-protection of the skin, and energy metabolism
Beneficial effects of vitamin D in regulating the immune response and its importance in protecting against autoimmune, infectious, and inflammatory diseases
The role vitamin D plays in the regulation of the aging process―including aspects of oxidative stress, senescence, and mortality, as well as its role in protection against cardiovascular disease and nervous system disorders
This book represents an important contribution toward understanding the mechanisms by which vitamin D promotes health, increasing awareness of the importance that vitamin D plays during development, at birth, and throughout the aging process. It is a valuable reference for researchers in academia, nutrition, medicine, and industry.

Oxidative Stress and Free Radical Damage in Neurology (Oxidative Stress in Applied Basic Research and Clinical Practice)

The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinsonís are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.

Cellular Health Mitochondria Epigenetics DNA Testing Microbiota Gut Health
Stress Health Enzyme Functional Medicine Nutrition Antioxidants Free Radicals Amino Acids
Inflammation Anti-Inflammatory Butyrate Supplements GI-tract Health Short Chain Fatty Acids SCFAs
Nucleotides Vitamins Minerals Vagus Nerve Nutritional Supplements Leaky-Gut IBS Irritable Bowel Syndrome
Microbiome Gut Lining Probiotics Prebiotics Health Supplements Gut Supplements
Gut Mind Health Fiber Neurology Digestion Detox-Cleansing Digestive Health Wellness
Supplements Immune System Abdominal Health Brain Health Stomach Health Gut Microbiome



Oxidative Stress Nutrition for Improving Health.